Akroprint is a tissue engineering startup developing a scalable, personalized solution for complete foreskin regeneration using advanced 3D bioprinting technologies.

Our approach combines innovations in biomaterials, digital modeling, and bioprinting to create tissue constructs that overcome the limitations of skin grafts, manual restoration, and donor-based tissue engineering methods. Akroprint’s long-term vision is to make a patentable solution widely available, medically sound, and accessible to the market of millions of men seeking circumcision reversal.

Circumcision is one of the most commonly performed surgeries in the world, but it is not a neutral event: circumcision results in permanent anatomical, sensory, and for many men, psychological changes. Existing options for restoration are limited, falling short in efficacy, accessibility, and/or long-term satisfaction. Based on market survey data, we estimate that the US demand for circumcision reversal stands at approximately 18 million men. We expect this figure to grow given current social trends and views on circumcision, and the global demand for circumcision outside the US further increases this market figure.

Akroprint challenges the assumption that nothing can be done about male genital cutting and its consequences. Akroprint is pioneering a new path in personalized regenerative medicine, one that acknowledges the depth of loss and seeks to restore form, function, and autonomy through innovative 3D bioprinting.

At its core, Akroprint exists to give men a real choice where none previously existed, and to offer hope and healing through science to the millions of men who demand it.

Akroprint is pioneering a scalable, personalized solution for foreskin regeneration using advanced 3D bioprinting—eliminating reliance on limited donor tissues and the shortcomings of traditional grafting techniques. We are the only company in the world seeking to create anatomically accurate, biologically compatible constructs that can be tailored to the individual, produced on demand, and deployed at scale.

What sets us further apart is our team’s unparalleled domain expertise: our founders include the corresponding author and two additional co-authors of the first peer-reviewed study on foreskin regeneration and bring over two decades of combined experience in this unique space. Akroprint is purpose-built to solve a long-overlooked problem with modern regenerative medicine. We merge scientific innovation with a mission to restore form, function, and autonomy for millions of men.

Akroprint’s primary research goal is to develop a fully functional, anatomically accurate foreskin using 3D bioprinting and regenerative tissue engineering. This includes building a scaffold that supports the regeneration of key structures such as the frenar band, mucosal epithelium, and specialized nerve endings—components that are not restored by existing methods.

Our research also aims to ensure the final product is safe, effective, customizable, and suitable for clinical application. This includes validating biocompatibility, refining printing techniques, and pursuing regulatory approval to ultimately bring this solution to market as a viable therapeutic option for circumcised men.

3D bioprinting offers a level of precision, scalability, and personalization that traditional tissue engineering methods cannot match. It enables the creation of complex, layered tissue structures that closely replicate natural anatomy—something especially important in areas like foreskin regeneration, where function and sensitivity matter greatly.

3D bioprinting allows Akroprint to produce consistent, patient-specific constructs at scale. It can bypass many ethical issues and impaired logistics tied to harvesting extremely limited human tissue from donor based approaches. Ultimately, 3D bioprinting provides a controllable, reproducible, and scalable path toward true regenerative therapies.

Akroprint’s founding team brings over two decades of combined experience working in the specialized field of foreskin regeneration. Three members co-authored the world’s first peer-reviewed paper on the topic. With deep expertise in both the science and the needs of the affected community, the team is united by a shared mission and proven ability to execute in this uniquely challenging space.

You can visit our team page here to learn more about our founders and current team.

We appreciate your interest and support. While Akroprint is currently being developed via private financing, we are only able to share investment-related materials with parties actively evaluating a potential alignment under applicable securities regulations. If that applies to you, feel free to contact us and we’ll follow up as appropriate.

In some cases, we may also be open to strategic advisory relationships. If you have relevant expertise or experience that may benefit the company, you’re welcome to reach out to share more about your background for consideration.

We plan to share public updates on our website as milestones are reached and major developments occur. You can also follow us on social media, where we’ll post news, educational content, and company updates. For those interested in partnership opportunities, feel free to reach out via our contact form—we’re happy to share more materials.

While highly limited in both scope and efficacy, most existing or proposed methods rely on either surgical grafting, manual skin expansion, or donor-derived tissues. Surgical grafts lack the specialized structures and sensitivity of a natural foreskin, while manual restoration requires years of effort and still cannot regenerate complex tissue like the frenulum, ridged band, and specialized nerve endings (although some mechanical and psychological benefits may be achieved). Surgical grafts suffer from the same setbacks and have notably low satisfaction rates. Donor-based approaches are not yet realized, but research into this pathway may face supply limitations related to scarcity of tissue, handling errors, and lack of personalization.

Akroprint takes a fundamentally different approach by using advanced 3D bioprinting and biomaterials science to engineer patient-specific tissue constructs. The underlying principles of this approach allows for the recreation of the anatomical, neurological, and vascular complexity of the foreskin with far greater precision than existing approaches. It also offers a scalable solution that overcomes the biological, ethical, and logistical limitations of donor-based options—making true regeneration not just possible, but accessible.

Developing new biotechnologies, particularly in regenerative medicine, is a complex and iterative process that requires both precision and patience. However, we share the sense of urgency needed to address the effects of circumcision felt by millions of men worldwide, and are aiming to bring our solution as quickly as possible. Our work is underway, and we’re committed to sharing key milestones as we achieve them. While we can’t provide an exact completion date at this stage, we’re taking deliberate steps to build a scalable, scientifically sound, and investor-ready pathway forward.